Neurotoxic effects of MPTP on mouse cerebral cortex: Modulation of neuroinflammation as a neuroprotective strategy

Parkinson's disease (PD) is a progressive neurological disorder, mainly characterized by the progressive loss of dopaminergic neurons in the Substantia nigra pars compacta (SNpc) and by the presence of intracellular inclusions, known as Lewy bodies. Despite SNpc being considered the primary aff...

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Bibliographic Details
Main Author: Mendes, Mariana Oliveira (author)
Other Authors: Rosa, Alexandra Isabel (author), Carvalho, Andreia Neves (author), Nunes, Maria João (author), Dionísio, Pedro (author), Rodrigues, Elsa (author), Costa, Daniela (author), Silva, Sara Carina Duarte (author), Maciel, P. (author), Rodrigues, Cecília Maria Pereira (author), Gama, Maria João (author), Castro-Caldas, Margarida (author)
Format: article
Language:eng
Published: 2019
Subjects:
Adenosine Triphosphate
Animals
Annexin A1
Anti-Inflammatory Agents
Cell Line
Cerebral Cortex
MPTP Poisoning
Male
Mice
Mice, Inbred C57BL
Microglia
NF-E2-Related Factor 2
Neuroprotective Agents
Protein Kinases
Taurochenodeoxycholic Acid
Ubiquitin-Protein Ligases
Parkinson's disease
TUDCA
ANXA1
Neuroinflammation
Ciências Médicas::Medicina Básica
Science & Technology
Online Access:http://hdl.handle.net/1822/62357
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/62357

Internet

http://hdl.handle.net/1822/62357

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