Metabolomic approaches in the discovery of potential urinary biomarkers of drug-induced liver injury (DILI)

Drug-induced liver injury (DILI) is a major safety issue during drug development, as well as the most common cause for the withdrawal of drugs from the pharmaceutical market. The identification of DILI biomarkers is a labor-intensive area. Conventional biomarkers are not specific and often only appe...

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Bibliographic Details
Main Author: Araújo, Ana Margarida (author)
Other Authors: Carvalho, Márcia (author), Carvalho, Félix (author), Bastos, Maria de Lourdes (author), Guedes de Pinho, Paula (author)
Format: article
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/10284/10036
Country:Portugal
Oai:oai:bdigital.ufp.pt:10284/10036