Association between EBV serological patterns and lymphocytic profile of SjS patients support a virally triggered autoimmune epithelitis

Sjögren's syndrome (SjS) is characterized by lymphocytic infiltration of exocrine glands, i.e. autoimmune epithelitis. Lymphocytes are central in SjS pathogenesis, with B-cell hyperactivity mediated by T-cells. B-cells are main targets of Epstein-Barr virus (EBV) infection, a frequently-suggest...

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Detalhes bibliográficos
Autor principal: Barcelos, F (author)
Outros Autores: Martins, C (author), Monteiro, R (author), Cardigos, J (author), Prussiani, T (author), Sítima, M (author), Alves, N (author), Vaz-Patto, JA (author), Cunha-Branco, J (author), Borrego, LM (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Texto completo:http://hdl.handle.net/10400.26/35738
País:Portugal
Oai:oai:comum.rcaap.pt:10400.26/35738