Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemal V-H+-ATPase

Breast cancer is the most common cancer in women worldwide. Metastatic breast cancer cells are known to display V-H+-ATPase at the plasma membrane, where it is involved in the acquisition of a more metastatic phenotype. Therefore, V-H+-ATPase emerged as a promising candidate for breast cancer therap...

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Bibliographic Details
Main Author: Cátia S. Pereira (author)
Other Authors: Guedes, J. (author), Gonçalves, Marília (author), Loureiro, Luís (author), Castro, Lisandra (author), Gerós, H. (author), Rodrigues, L. R. (author), Côrte-Real, Manuela (author)
Format: conferenceObject
Language:eng
Published: 2016
Subjects:
Lactoferrin
V-H+-ATPase
Breast cancer
V-H+-ATPase inhibitor
Extracellular acidification rate
Online Access:http://hdl.handle.net/1822/44036
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/44036

Internet

http://hdl.handle.net/1822/44036

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