Inhibitors of calpain activation (PD150606 and E-64) and renal ischemia-reperfusion injury

Calpain activation has been implicated in the development of ischemia-reperfusion (I-R) injury. Here we investigate the effects of two inhibitors of calpain activity, PD150606 and E-64, on the renal dysfunction and injury caused by I-R of rat kidneys in vivo. Male Wistar rats were administered PD150...

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Detalhes bibliográficos
Autor principal: Chatterjee, PK (author)
Outros Autores: Todorovic, Z (author), Sivarajah, A (author), Mota-Filipe, H (author), Brown, PAJ (author), Stewart, KN (author), Mazzon, E (author), Cuzzocrea, S (author), Thiemermann, C (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Pharmacology & Pharmacy
Texto completo:http://hdl.handle.net/10451/21231
País:Portugal
Oai:oai:repositorio.ul.pt:10451/21231

Texto Completo

http://hdl.handle.net/10451/21231

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