Lipid-based Nanocarriers for siRNA Delivery: Challenges, Strategies and the Lessons Learned from the DODAX: MO Liposomal System

The possibility of using the RNA interference (RNAi) mechanisms in gene therapy was one of the scientific breakthroughs of the last century. Despite the extraordinary therapeutic potential of this approach, the need for an efficient gene carrier is hampering the translation of the RNAi technology to...

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Bibliographic Details
Main Author: Oliveira, Ana C. N. (author)
Other Authors: Fernandes, Joana (author), Gonçalves, Anabela (author), Andreia C. Gomes (author), Real Oliveira, M. Elisabete C.D. (author), Gomes, Andreia C (author)
Format: article
Language:eng
Published: 2019
Subjects:
Cationic liposomes
monoolein
siRNA delivery
DODAB
DODAC
PEGylation
Science & Technology
Online Access:http://hdl.handle.net/1822/55931
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/55931

Internet

http://hdl.handle.net/1822/55931

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