Aromatic carbohydrate amphiphile disrupts cancer spheroids and prevents relapse

Spheroids recapitulate the organization, heterogeneity and microenvironment of solid tumors. Herein, we targeted spatiotemporally the accelerated metabolism of proliferative cells located on the spheroid surface that ensure structure maintenance and/or growth. We demonstrate that phosphorylated carb...

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Bibliographic Details
Main Author: Brito, Alexandra Manuela Fernandes (author)
Other Authors: Pereira, P. M. R. (author), Reis, R. L. (author), Ulijn, R. V. (author), Lewis, J. S. (author), Pires, R. A. (author), Pashkuleva, I. (author)
Format: article
Language:eng
Published: 2020
Subjects:
3D cancer models
Biocatalytic self-assembly
Chemotherapy
GLUT1
Glycolysis
Ciências Médicas::Biotecnologia Médica
Science & Technology
Online Access:https://hdl.handle.net/1822/66987
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/66987

Internet

https://hdl.handle.net/1822/66987

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