Efficient conversion of 6-cyanopurines into 6-alkoxyformimidoyl purines

An extremely simple method for the selective synthesis of 9-aryl and 9-alkyl 6-alkoxy or 6-alkoxyformimidoyl purines from the corresponding 6-cyanopurines is described. The reaction is carried out with methanol or ethanol in the presence of DBU. At room temperature, nucleophilic attack by the primar...

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Detalhes bibliográficos
Autor principal: Carvalho, M. Alice (author)
Outros Autores: Esteves, Teresa M. (author), Proença, M. Fernanda R. P. (author), Booth, Brian L. (author)
Formato: article
Idioma:eng
Publicado em: 2004
Assuntos:
Texto completo:http://hdl.handle.net/1822/2197
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/2197