Efficient conversion of 6-cyanopurines into 6-alkoxyformimidoyl purines

An extremely simple method for the selective synthesis of 9-aryl and 9-alkyl 6-alkoxy or 6-alkoxyformimidoyl purines from the corresponding 6-cyanopurines is described. The reaction is carried out with methanol or ethanol in the presence of DBU. At room temperature, nucleophilic attack by the primar...

Full description

Bibliographic Details
Main Author: Carvalho, M. Alice (author)
Other Authors: Esteves, Teresa M. (author), Proença, M. Fernanda R. P. (author), Booth, Brian L. (author)
Format: article
Language:eng
Published: 2004
Subjects:
Online Access:http://hdl.handle.net/1822/2197
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/2197