Valproate induces in vitro accumulation of long-chain fatty acylcarnitines
To elucidate the interference mechanisms of valproate (VPA) with mitochondrial fatty acid beta -oxidation (FAO), the profile of acylcarnitine formation was studied in vitro. Human fibroblasts were incubated with 0.2 mmol/L [U-C-13]palmitate, 0.4 mmol/L L-
Main Author: | |
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Other Authors: | , , , |
Format: | article |
Language: | eng |
Published: |
2015
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Subjects: | |
Online Access: | http://hdl.handle.net/10451/21330 |
Country: | Portugal |
Oai: | oai:repositorio.ul.pt:10451/21330 |