Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
The presence of aberrant number of centrioles is a recognized cause of aneuploidy and hallmark of cancer. Hence, centriole duplication needs to be tightly regulated. It has been proposed that centriole separation limits centrosome duplication. The mechanism driving centriole separation is poorly und...
| Main Author: | |
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| Other Authors: | , , , , , , |
| Format: | article |
| Language: | eng |
| Published: |
2019
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| Online Access: | https://hdl.handle.net/10216/136235 |
| Country: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/136235 |