Acto-myosin force organization modulates centriole separation and PLK4 recruitment to ensure centriole fidelity
The presence of aberrant number of centrioles is a recognized cause of aneuploidy and hallmark of cancer. Hence, centriole duplication needs to be tightly regulated. It has been proposed that centriole separation limits centrosome duplication. The mechanism driving centriole separation is poorly und...
| Autor principal: | |
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| Outros Autores: | , , , , , , |
| Formato: | article |
| Idioma: | eng |
| Publicado em: |
2019
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| Texto completo: | https://hdl.handle.net/10216/136235 |
| País: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/136235 |