Uncovering the binding of the anticancer small molecule SLMP53-1 to mutant p53R280K

Introduction: The tumor suppressor protein p53 is frequently mutated in human cancer, which is commonly related to poor prognosis. Thus, reactivation of wild-type functions to mutant p53 is an attractive anticancer therapeutic strategy (1). Indeed, many efforts have been developed to target mutant p...

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Detalhes bibliográficos
Autor principal: Gomes, A. S. (author)
Outros Autores: Gomes, S. (author), Soares, Joana (author), Ramos, Helena (author), Oliveira, Carla (author), Freire, Filipe (author), Pinheiro, Benedita (author), Marcelo, Filipa (author), Espadinha, Margarida (author), Domingues, Lucília (author), Romão, Maria João (author), Carvalho, Ana Luísa (author), Santos, Maria M. M. (author), Saraiva, Lucília (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2017
Texto completo:http://hdl.handle.net/1822/45047
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/45047

Texto Completo

http://hdl.handle.net/1822/45047

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