Uncovering the binding of the anticancer small molecule SLMP53-1 to mutant p53R280K

Introduction: The tumor suppressor protein p53 is frequently mutated in human cancer, which is commonly related to poor prognosis. Thus, reactivation of wild-type functions to mutant p53 is an attractive anticancer therapeutic strategy (1). Indeed, many efforts have been developed to target mutant p...

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Bibliographic Details
Main Author: Gomes, A. S. (author)
Other Authors: Gomes, S. (author), Soares, Joana (author), Ramos, Helena (author), Oliveira, Carla (author), Freire, Filipe (author), Pinheiro, Benedita (author), Marcelo, Filipa (author), Espadinha, Margarida (author), Domingues, Lucília (author), Romão, Maria João (author), Carvalho, Ana Luísa (author), Santos, Maria M. M. (author), Saraiva, Lucília (author)
Format: conferenceObject
Language:eng
Published: 2017
Online Access:http://hdl.handle.net/1822/45047
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/45047

Internet

http://hdl.handle.net/1822/45047

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