Deciphering the pathways leading to the enhancement of NIS transcription in thyroid tissue

The sodium-iodide symporter (NIS) is expressed in the basolateral membrane of thyroid follicular cells and transports iodide into its interior. Its expression in thyroid cancers allows the use of radioactive iodine (RAI) as a therapeutic tool. Unfortunately, a significant proportion of patients lose...

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Bibliographic Details
Main Author: Paixão, Francisca Ventura (author)
Format: masterThesis
Language:eng
Published: 2022
Subjects:
Sodium iodide symporter
Thyroid carcinoma
Radioactive iodine
PI3K/Akt/mTOR
NF-κB
Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias
Online Access:http://hdl.handle.net/10362/69909
Country:Portugal
Oai:oai:run.unl.pt:10362/69909

Internet

http://hdl.handle.net/10362/69909

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