Deciphering the pathways leading to the enhancement of NIS transcription in thyroid tissue

The sodium-iodide symporter (NIS) is expressed in the basolateral membrane of thyroid follicular cells and transports iodide into its interior. Its expression in thyroid cancers allows the use of radioactive iodine (RAI) as a therapeutic tool. Unfortunately, a significant proportion of patients lose...

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Detalhes bibliográficos
Autor principal: Paixão, Francisca Ventura (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2022
Assuntos:
Sodium iodide symporter
Thyroid carcinoma
Radioactive iodine
PI3K/Akt/mTOR
NF-κB
Domínio/Área Científica::Engenharia e Tecnologia::Outras Engenharias e Tecnologias
Texto completo:http://hdl.handle.net/10362/69909
País:Portugal
Oai:oai:run.unl.pt:10362/69909

Texto Completo

http://hdl.handle.net/10362/69909

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