Antisense locked nucleic acid gapmers to control Candida albicans filamentation

Whereas locked nucleic acid (LNA) has been extensively used to control gene expression, it has never been exploited to control Candida virulence genes. Thus, the main goal of this work was to compare the efficacy of five different LNA-based antisense oligonucleotides (ASO) with respect to the abilit...

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Bibliographic Details
Main Author: Araújo, Daniela (author)
Other Authors: Mil-Homens, Dalila (author), Rodrigues, M. Elisa (author), Henriques, Mariana (author), Jørgensen, Per Trolle (author), Wengel, Jesper (author), Silva, Sónia Carina (author)
Format: article
Language:eng
Published: 2022
Subjects:
Antisense oligonucleotides
Locked nucleic acid
Candidiasis
Filamentation
Galleria mellonella
Ciências Naturais::Ciências Biológicas
Science & Technology
Online Access:https://hdl.handle.net/1822/74493
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/74493

Internet

https://hdl.handle.net/1822/74493

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