Antisense locked nucleic acid gapmers to control Candida albicans filamentation

Whereas locked nucleic acid (LNA) has been extensively used to control gene expression, it has never been exploited to control Candida virulence genes. Thus, the main goal of this work was to compare the efficacy of five different LNA-based antisense oligonucleotides (ASO) with respect to the abilit...

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Detalhes bibliográficos
Autor principal: Araújo, Daniela (author)
Outros Autores: Mil-Homens, Dalila (author), Rodrigues, M. Elisa (author), Henriques, Mariana (author), Jørgensen, Per Trolle (author), Wengel, Jesper (author), Silva, Sónia Carina (author)
Formato: article
Idioma:eng
Publicado em: 2022
Assuntos:
Antisense oligonucleotides
Locked nucleic acid
Candidiasis
Filamentation
Galleria mellonella
Ciências Naturais::Ciências Biológicas
Science & Technology
Texto completo:https://hdl.handle.net/1822/74493
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/74493

Texto Completo

https://hdl.handle.net/1822/74493

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