Ultrasound-assisted biosynthesis of novel methotrexate-conjugates

New methotrexate-acylglycerols and methotrexate-cyclodextrins (, and -CD) conjugates were obtained via esterification or transesterification reactions. All reactions were catalysed by esterases namely immobilized Lipase from Candida antarctica B and Lipase from Thermomyces lanuginosus. The use of ul...

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Bibliographic Details
Main Author: Noro, Jennifer Martins (author)
Other Authors: Reis, R. L. (author), Cavaco-Paulo, Artur (author), Silva, Carla (author)
Format: article
Language:eng
Published: 2018
Subjects:
Biosynthesis
Lipases
Ultrasound
Methotrexate
triacylglycerols
cyclodextrins
Science & Technology
Online Access:http://hdl.handle.net/1822/55082
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/55082

Internet

http://hdl.handle.net/1822/55082

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