How do Candida glabrata´s biofilms respond to antifungal drugs?

Candida species are responsible for recurrent human infections, mostly in immunocompromised patients, due to their high vulnerability. Candida glabrata has been shown to have a major role in these infections being the second most prevalent species involved in human fungemia. Objective: To understand...

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Detalhes bibliográficos
Autor principal: Rodrigues, Célia Fortuna (author)
Outros Autores: Rodrigues, E. (author), Silva, Sónia Carina (author), Azeredo, Joana (author), Henriques, Mariana (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2015
Assuntos:
Texto completo:http://hdl.handle.net/1822/37878
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/37878
Descrição
Resumo:Candida species are responsible for recurrent human infections, mostly in immunocompromised patients, due to their high vulnerability. Candida glabrata has been shown to have a major role in these infections being the second most prevalent species involved in human fungemia. Objective: To understand the effect of three different antifungal agents Fluconazole (Flu), Amphotericin B (AmB) and Caspofungin (Csf) - in C. glabratas biofilm formation, specially their role on matrix composition.