Mitochondrially-mediated toxicity of bile acids
In the healthy hepatocyte, uptake of bile acids across the basolateral membrane and export via the canalicular export pump, are tightly coupled. Impairment of bile formation or excretion results in cholestasis, characterized by accumulation of bile acids in systemic blood and within the hepatocyte....
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| Formato: | article |
| Idioma: | eng |
| Publicado em: |
2004
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| Texto completo: | http://hdl.handle.net/10316/5378 |
| País: | Portugal |
| Oai: | oai:estudogeral.sib.uc.pt:10316/5378 |