Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation
Centrosomes are the major microtubule organising centres of animal cells. Deregulation in their number occurs in cancer and was shown to trigger tumorigenesis in mice. However, the incidence, consequence and origins of this abnormality are poorly understood. Here, we screened the NCI-60 panel of hum...
Autor principal: | |
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Outros Autores: | , , , , , , , , , , , , , , , , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2018
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Texto completo: | https://hdl.handle.net/10216/127072 |
País: | Portugal |
Oai: | oai:repositorio-aberto.up.pt:10216/127072 |