Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation

Alzheimer's disease (AD) is the most common form of dementia in the elderly individuals, resulting from a complex interaction between environmental and genetic factors. Impaired brain iron homeostasis has been recognized as an important mechanism underlying the pathogenesis of this disease. Nev...

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Bibliographic Details
Main Author: Crespo, A (author)
Other Authors: Silva, B (author), Marques, L (author), Marcelino, E (author), Maruta, C (author), Costa, S (author), Timóteo, A (author), Vilares, A (author), Couto, F (author), Faustino, P (author), Correia, AP (author), Verdelho, A (author), Porto, G (author), Guerreiro, M (author), Herrero Valverde, A (author), Costa, C (author), Mendonça, A (author), Costa, L (author), Martins, M (author)
Format: article
Language:eng
Published: 2015
Subjects:
Alzheimer disease
Aged
Homeostasis
Brain
Iron
Online Access:http://hdl.handle.net/10400.10/1515
Country:Portugal
Oai:oai:repositorio.hff.min-saude.pt:10400.10/1515

Internet

http://hdl.handle.net/10400.10/1515

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