Ceramides bind VDAC2 to trigger mitochondrial apoptosis

Ceramides draw wide attention as tumor suppressor lipids that act directly on mitochondria to trigger apoptotic cell death. However, molecular details of the underlying mechanism are largely unknown. Using a photoactivatable ceramide probe, we here identify the voltage-dependent anion channels VDAC1...

Full description

Bibliographic Details
Main Author: Dadsena, Shashank (author)
Other Authors: Bockelmann, Svenja (author), Mina, John G.M. (author), Hassan, Dina G. (author), Korneev, Sergei (author), Razzera, Guilherme (author), Jahn, Helene (author), Niekamp, Patrick (author), Müller, Dagmar (author), Schneider, Markus (author), Tafesse, Fikadu G. (author), Marrink, Siewert J. (author), Melo, Manuel N. (author), Holthuis, Joost C.M. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Chemistry(all)
Biochemistry, Genetics and Molecular Biology(all)
Physics and Astronomy(all)
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/92533
Country:Portugal
Oai:oai:run.unl.pt:10362/92533

Internet

http://hdl.handle.net/10362/92533

Similar Items