Controlled delivery of gold nanoparticle-coupled miRNA therapeutics via an injectable self-healing hydrogel

Differential expression of microRNAs (miRNAs) plays a role in many diseases, including cancer and cardiovascular diseases. Potentially, miRNAs could be targeted with miRNA-therapeutics. Sustained delivery of these therapeutics remains challenging. This study couples miR-mimics to PEG-peptide gold na...

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Bibliographic Details
Main Author: van der Ven, Casper F T (author)
Other Authors: Tibbitt, Mark W (author), Conde, João (author), van Mil, Alain (author), Hjortnaes, Jesper (author), Doevendans, Pieter A (author), Sluijter, Joost P G (author), Aikawa, Elena (author), Langer, Robert S (author)
Format: article
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/10362/128611
Country:Portugal
Oai:oai:run.unl.pt:10362/128611