Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Alzheimer's disease (AD) is a neurodegenerative disorder of still unknown etiology and the leading cause of dementia worldwide. Besides its main neuropathological hallmarks, a dysfunctional homeostasis of transition metals has been reported to play a pivotal role in the pathogenesis of this dis...

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Bibliographic Details
Main Author: Guerreiro, Cláudia (author)
Other Authors: Silva, Bruno (author), Crespo, Ângela (author), Marques, Liliana (author), Costa, Sónia (author), Timóteo, Ângela (author), Marcelino, Erica (author), Maruta, Carolina (author), Vilares, Arminda (author), Matos, Mafalda (author), Couto, Frederico S. (author), Faustino, Paula (author), Verdelho, Ana (author), Guerreiro, Manuela (author), Herrero, Ana (author), Costa, Cristina (author), de Mendonça, Alexandre (author), Martins, Madalena (author), Costa, Luciana (author)
Format: article
Language:eng
Published: 2015
Subjects:
Alzheimer's Disease
Cellular Iron Export
Gene Expression
Iron Homeostasis
Determinantes Imunológicos em Doenças Crónicas
Doenças Genéticas
Online Access:http://hdl.handle.net/10400.18/3112
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/3112

Internet

http://hdl.handle.net/10400.18/3112

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