Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Alzheimer's disease (AD) is a neurodegenerative disorder of still unknown etiology and the leading cause of dementia worldwide. Besides its main neuropathological hallmarks, a dysfunctional homeostasis of transition metals has been reported to play a pivotal role in the pathogenesis of this dis...

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Detalhes bibliográficos
Autor principal: Guerreiro, Cláudia (author)
Outros Autores: Silva, Bruno (author), Crespo, Ângela (author), Marques, Liliana (author), Costa, Sónia (author), Timóteo, Ângela (author), Marcelino, Erica (author), Maruta, Carolina (author), Vilares, Arminda (author), Matos, Mafalda (author), Couto, Frederico S. (author), Faustino, Paula (author), Verdelho, Ana (author), Guerreiro, Manuela (author), Herrero, Ana (author), Costa, Cristina (author), de Mendonça, Alexandre (author), Martins, Madalena (author), Costa, Luciana (author)
Formato: article
Idioma:eng
Publicado em: 2015
Assuntos:
Alzheimer's Disease
Cellular Iron Export
Gene Expression
Iron Homeostasis
Determinantes Imunológicos em Doenças Crónicas
Doenças Genéticas
Texto completo:http://hdl.handle.net/10400.18/3112
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/3112

Texto Completo

http://hdl.handle.net/10400.18/3112

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