6-Carbohydrazonamidepurines: Convenient Precursors for 4,8-Disubstituted Pyrimido[5,4-d] pyrimidines

A series of 4-arylamino-8-(alkyl or aryl)hydrazidepyrimido[5,4-d]pyrimidines was obtained efficiently from 6-carbohydrazonamidepurines by reaction with piperidine. The 6-carbo-hydrazonamidepurines were generated selectively by the reaction of 6-imidatopurine with hydrazides under acidic conditions.

Bibliographic Details
Main Author: Rocha, Ashly (author)
Other Authors: Bacelar, Ana H. (author), Fernandes, Joana (author), Proença, M. Fernanda R. P. (author), Carvalho, M. Alice (author)
Format: article
Language:eng
Published: 2014
Subjects:
Rearrangement
Ring opening
Ring closure
Substituent effects
Fused-ring systems
Heterocycles
Ciências Naturais::Ciências Químicas
Science & Technology
Online Access:http://hdl.handle.net/1822/72750
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/72750

Internet

http://hdl.handle.net/1822/72750

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