6-Carbohydrazonamidepurines: Convenient Precursors for 4,8-Disubstituted Pyrimido[5,4-d] pyrimidines

A series of 4-arylamino-8-(alkyl or aryl)hydrazidepyrimido[5,4-d]pyrimidines was obtained efficiently from 6-carbohydrazonamidepurines by reaction with piperidine. The 6-carbo-hydrazonamidepurines were generated selectively by the reaction of 6-imidatopurine with hydrazides under acidic conditions.

Detalhes bibliográficos
Autor principal: Rocha, Ashly (author)
Outros Autores: Bacelar, Ana H. (author), Fernandes, Joana (author), Proença, M. Fernanda R. P. (author), Carvalho, M. Alice (author)
Formato: article
Idioma:eng
Publicado em: 2014
Assuntos:
Texto completo:http://hdl.handle.net/1822/72750
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/72750