REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia

The hypoxia-inducible factor (HIF) is a key regulator of the cellular response to hypoxia which promotes oxygen delivery and metabolic adaptation to oxygen deprivation. However, the degree and duration of HIF-1α expression in hypoxia must be carefully balanced within cells in order to avoid unwanted...

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Bibliographic Details
Main Author: Cavadas, Miguel A. S. (author)
Other Authors: Mesnieres, Marion (author), Crifo, Bianca (author), Manresa, Mario C. (author), Selfridge, Andrew C. (author), Scholz, Carsten C. (author), Cummins, Eoin P. (author), Cheong, Alex (author), Taylor, Cormac T. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Gene regulation
Transcriptional regulatory elements
Online Access:http://hdl.handle.net/10400.7/533
Country:Portugal
Oai:oai:arca.igc.gulbenkian.pt:10400.7/533

Internet

http://hdl.handle.net/10400.7/533

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