Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene

BACKGROUND Plasmodium falciparum, has developed resistance to many of the drugs in use. The recommended treatment policy is now to use drug combinations. The atovaquone-proguanil (AP) drug combination, is one of the treatment and prophylaxis options. Atovaquone (ATQ) exerts its action by inhibiting...

ver descrição completa

Detalhes bibliográficos
Autor principal: Afonso, Ana Júlia Pinto Fonseca Sieuve (author)
Outros Autores: Neto, Z (author), Castro , H (author), Ferreira, Dinora (author), Alves, AC (author), Tomás , AM (author), Rosário, Virgilio Estólio do (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Texto completo:http://hdl.handle.net/10362/117175
País:Portugal
Oai:oai:run.unl.pt:10362/117175