Dual ligand immunoliposomes for drug delivery to the brain

Drug delivery systems that can reach brain areas affected by amyloid deposits are still underdeveloped. We propose pegylated liposomes functionalized with two antibodies, the anti-transferrin receptor monoclonal antibody (0X26MAb) and the anti-amyloid beta peptide antibody (19B8MAb), as nanocarriers...

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Bibliographic Details
Main Author: Joana A. Loureiro (author)
Other Authors: Bárbara Gomes (author), Gert Fricker (author), Isabel Cardoso (author), Carlos A. Ribeiro (author), Cristiana Gaiteiro (author), Manuel A. N. Coelho (author), Sandra Rocha (author), Maria do Carmo Pereira (author)
Format: article
Language:eng
Published: 2015
Online Access:https://hdl.handle.net/10216/104490
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/104490