Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus as potential antimalarial prodrugs
Primaquine dipeptide derivatives bearing an imidazolidin-4-one moiety at the N-terminus were synthesized and evaluated as potential transmission-blocking antimalarial prodrugs. All compounds were hydrolyzed to the parent dipeptide derivative of primaquine in neutral and basic solutions, with half li...
Autor principal: | |
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Outros Autores: | , , , |
Formato: | article |
Idioma: | eng |
Publicado em: |
2015
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Assuntos: | |
Texto completo: | http://hdl.handle.net/10451/21520 |
País: | Portugal |
Oai: | oai:repositorio.ul.pt:10451/21520 |