LPS induction of I kappa B-alpha degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, Tyrphostin b42

The Janus kinase (JAK) family of protein tyrosine kinases are activated in response to a wide variety of external stimuli. Here we have investigated whether the janus kinase 2 (JAK2) is involved in the induction of nitric oxide synthase type II (iNOS) expression in a mouse fetal skin dendritic cell...

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Detalhes bibliográficos
Autor principal: Cruz, MT (author)
Outros Autores: Duarte, CB (author), Gonçalo, Margarida (author), Carvalho, AP (author), Lopes, MC (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Células Dendríticas
Lipopolissacáridos
Pele
Proteínas I-kappa B
Proteínas Proto-Oncogénicas
Sintetase de Óxido Nítrico
Texto completo:http://hdl.handle.net/10400.4/750
País:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/750

Texto Completo

http://hdl.handle.net/10400.4/750

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