LPS induction of I kappa B-alpha degradation and iNOS expression in a skin dendritic cell line is prevented by the janus kinase 2 inhibitor, Tyrphostin b42

The Janus kinase (JAK) family of protein tyrosine kinases are activated in response to a wide variety of external stimuli. Here we have investigated whether the janus kinase 2 (JAK2) is involved in the induction of nitric oxide synthase type II (iNOS) expression in a mouse fetal skin dendritic cell...

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Bibliographic Details
Main Author: Cruz, MT (author)
Other Authors: Duarte, CB (author), Gonçalo, Margarida (author), Carvalho, AP (author), Lopes, MC (author)
Format: article
Language:eng
Published: 2010
Subjects:
Células Dendríticas
Lipopolissacáridos
Pele
Proteínas I-kappa B
Proteínas Proto-Oncogénicas
Sintetase de Óxido Nítrico
Online Access:http://hdl.handle.net/10400.4/750
Country:Portugal
Oai:oai:rihuc.huc.min-saude.pt:10400.4/750

Internet

http://hdl.handle.net/10400.4/750

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