The LacZ plasmid-based transgenic mouse model: an integrative approach to study the genotoxicity of nanomaterials

Numerous in vitro studies have been performed to address the potential genotoxicity of chemicals and of emerging products, e.g., nanomaterials. Although valuable for hazard assessment, the in vitro assays do not reflect the complexity of an organism, including, bioavailability, toxicokinetics and im...

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Bibliographic Details
Main Author: Louro, Henriqueta (author)
Other Authors: Pinto, Miguel (author), Vital, Nádia (author), Tavares, Ana (author), Costa, Pedro M. (author), Silva, Maria João (author)
Format: bookPart
Language:eng
Published: 2014
Subjects:
Genotoxicidade Ambiental
In vivo Genotoxicity Testing
Histopathology
Integrative
Nanomaterials
Micronucleus Assay
Comet Assay
LacZ Mutations
Online Access:http://hdl.handle.net/10400.18/2453
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/2453

Internet

http://hdl.handle.net/10400.18/2453

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