Cell encapsulated hydrogel microspheres as "building blocks" for producing 3D constructs

Cell encapsulation within hydrogel microspheres shows great promise in the field of tissue engineering and regenerative medicine (TERM). However, the assembling of microspheres as building blocks to produce complex tissues is a hard task because of their inability to place along length scales in spa...

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Bibliographic Details
Main Author: Praveen, S. (author)
Other Authors: Correia, C. R. (author), Mano, J. F. (author)
Format: conferenceObject
Language:eng
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/1822/41640
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/41640
Description
Summary:Cell encapsulation within hydrogel microspheres shows great promise in the field of tissue engineering and regenerative medicine (TERM). However, the assembling of microspheres as building blocks to produce complex tissues is a hard task because of their inability to place along length scales in space. We propose a proof-of-concept strategy to produce 3D constructs using cell encapsulated as building blocks by perfusion based LbL technique. This technique exploits the â bindingâ potential of multilayers apart from coating