Gamma interferon-induced T-cell loss in virulent Mycobacterium avium infection

Infection by virulent Mycobacterium avium caused progressive severe lymphopenia in C57BL/6 mice due to increased apoptosis rates. T-cell depletion did not occur in gamma interferon (IFN-gamma)-deficient mice which showed increased T-cell numbers and proliferation; in contrast, deficiency in nitric o...

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Bibliographic Details
Main Author: Florido, M (author)
Other Authors: Pearl, JE (author), Solache, A (author), Borges, M (author), Haynes, L (author), Cooper, AM (author), Appelberg, R (author)
Format: article
Language:eng
Published: 2005
Subjects:
Online Access:https://hdl.handle.net/10216/69096
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/69096