Hybrid dynamic modeling of Escherichia coli central metabolic network combining Michaelis–Menten and approximate kinetic equations

The construction of dynamic metabolic models at reaction network level requires the use of mechanistic enzymatic rate equations that comprise a large number of parameters. The lack of knowledge on these equations and the difficulty in the experimental identification of their associated parameters, r...

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Detalhes bibliográficos
Autor principal: Costa, Rafael S. (author)
Outros Autores: Machado, C. D. (author), Rocha, I. (author), Ferreira, Eugénio C. (author)
Formato: article
Idioma:eng
Publicado em: 2010
Assuntos:
Texto completo:https://hdl.handle.net/1822/10690
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/10690