Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splice variant RAC1B in colorectal cells

A major risk factor promoting tumor development is chronic inflammation and the use of nonsteroidal anti-inflammatory drugs (NSAID), including ibuprofen, can decrease the risk of developing various types of cancer, including colorectal cancer (CRC). Although the molecular mechanism behind the antitu...

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Bibliographic Details
Main Author: Gonçalves, Vânia (author)
Format: conferenceObject
Language:eng
Published: 2022
Subjects:
Ibuprofen
Alternative Splicing
RAC1B
Protein Kinase
SRPK
Vias de Transdução de Sinal e Patologias Associadas
Online Access:http://hdl.handle.net/10400.18/7974
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7974

Internet

http://hdl.handle.net/10400.18/7974

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