Aneuploidy and high S-phase as biomarkers of poor clinical outcome in poorly differentiated and anaplastic thyroid carcinoma

This study aimed to investigate the prognostic influence of DNA flow cytometry and RAS gene mutations in patients with poorly differentiated (PDTC) and anaplastic thyroid carcinoma (ATC). The series consisted of 26 patients with PDTC and ATC, and a median follow-up of 10 months (range 1-138). DNA pl...

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Bibliographic Details
Main Author: Pinto, António E. (author)
Other Authors: Silva, Giovani (author), Banito, Ana (author), Leite, Valeriano (author), Soares, Jorge (author)
Format: article
Language:eng
Published: 2022
Subjects:
Anaplastic thyroid carcinoma
DNA ploidy
Poorly differentiated thyroid carcinoma
Prognosis
RAS mutations
S-phase fraction
Cancer Research
Oncology
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/142149
Country:Portugal
Oai:oai:run.unl.pt:10362/142149

Internet

http://hdl.handle.net/10362/142149

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