Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance

Metagenomic next-generation sequencing (mNGS), the shotgun sequencing of RNA and DNA from clinical samples, has proved useful for broad-spectrum pathogen detection and the genomic surveillance of viral outbreaks. An additional target enrichment step is generally needed for high-sensitivity pathogen...

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Bibliographic Details
Main Author: Deng, X. (author)
Other Authors: Achari, A. (author), Federman, S. (author), Yu, G. (author), Somasekar, S. (author), Bártolo, I. (author), Yagi, S. (author), Mbala-Kingebeni, P. (author), Kapetshi, J. (author), Ahuka-Mundeke, S. (author), Muyembe-Tamfum, J. J. (author), Ahmed, A. A. (author), Ganesh, V. (author), Tamhankar, M. (author), Patterson, J. L. (author), Ndembi, N. (author), Mbanya, D. (author), Kaptue, L. (author), McArthur, C. (author), Muñoz-Medina, J. E. (author), Gonzalez-Bonilla, C. R. (author), López, S. (author), Arias, C. F. (author), Arevalo, S. (author), Miller, S. (author), Stone, M. (author), Busch, M. (author), Hsieh, K. (author), Messenger, S. (author), Wadford, D. A. (author), Rodgers, M. (author), Cloherty, G. (author), Faria, N. R. (author), Thézé, J. (author), Pybus, O. G. (author), Neto, Z. (author), Morais, J. (author), Taveira, N. (author), Hackett, J. Jr (author), Chiu, C. Y. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Infectious diseases
Metagenomics
Infectious-disease diagnostics
Microbial genetics
Virology
Online Access:http://hdl.handle.net/10400.26/33745
Country:Portugal
Oai:oai:comum.rcaap.pt:10400.26/33745

Internet

http://hdl.handle.net/10400.26/33745

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