Naphtho[2,3-d]isoxazole-4,9-dione-3-carboxylates: Potent, Non-cytotoxic, Antiapoptotic Agents

Compounds containing a quinone moiety represent an important class of biologically active molecules that are widespread in nature, displaying anticancer, antibacterial, antimalarial, and fungicidal activities. In the course of designing 2,3-disubstituted-1,4-naphthoquinones derivatives as potential...

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Bibliographic Details
Main Author: Santos, Daniela M. (author)
Other Authors: Santos, Maria M. M. (author), Viana, Ricardo J. S. (author), Castro, Rui E. (author), Moreira, Rui (author), Rodrigues, Cecília M. P. (author)
Format: article
Language:eng
Published: 2011
Subjects:
Apoptosis
Bcl-XL
Caspases
Hepatocytes
Naphthoquinone derivatives
Online Access:http://hdl.handle.net/10451/3847
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/3847

Internet

http://hdl.handle.net/10451/3847

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