Photonic modulation of EGFR: 280nm low level light arrests cancer cell activation and migration

Overexpression of the Epidermal Growth Factor Receptor (EGFR) by cancer cells is associated with a poor prognosis for the patient. For several decades, therapies targeting EGFR have been designed, including the use of monoclonal antibodies and small molecule tyrosine kinase inhibitors. The use of th...

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Bibliographic Details
Main Author: Botelho, C. M. (author)
Other Authors: Marques, Rogério Filipe Fernandes (author), Viruthachalam, Thiagarajan (author), Gonçalves, Odete Sofia Lopes (author), Vorum, Henrik (author), Gomes, Andreia C. (author), Neves-Petersen, Maria Teresa (author)
Format: conferencePaper
Language:eng
Published: 2017
Subjects:
Epidermal growth factor receptor
Activation
Arrest
EGFR
EGF
Cancer cells
Photonic Therapy
Cell Migration
Filopodia
Ciências Naturais::Ciências Biológicas
Science & Technology
Online Access:http://hdl.handle.net/1822/45162
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/45162

Internet

http://hdl.handle.net/1822/45162

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