New thienylpyrrolyl-cyanoacetic acid derivatives: synthesis and evaluation of the optical and solvatochromic properties
The novel thienylpyrrolyl-cyanoacetic acid derivatives were obtained in good yields through a simple Knoevenagel condensation of the corresponding precursor aldehydes with cyanoacetic acid in acetonitrile at reflux, using piperidine as catalyst. The formyl precursors 1-2 were obtained through two di...
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| Other Authors: | , |
| Format: | conferencePaper |
| Language: | eng |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://hdl.handle.net/1822/48515 |
| Country: | Portugal |
| Oai: | oai:repositorium.sdum.uminho.pt:1822/48515 |
| Summary: | The novel thienylpyrrolyl-cyanoacetic acid derivatives were obtained in good yields through a simple Knoevenagel condensation of the corresponding precursor aldehydes with cyanoacetic acid in acetonitrile at reflux, using piperidine as catalyst. The formyl precursors 1-2 were obtained through two different methods: (i) lithiation followed by treatment with DMF and (ii) Suzuki cross-coupling reaction. The novel push-pull systems were completely characterized by the usual spectroscopic techniques and the optical and solvatochromic properties were evaluated. |
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