Cell fate potentials and switching kinetics uncovered in a classic bistable genetic switch
Bistable switches are common gene regulatory motifs directing two mutually exclusive cell fates. Theoretical studies suggest that bistable switches are sufficient to encode more than two cell fates without rewiring the circuitry due to the non-equilibrium, heterogeneous cellular environment. However...
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| Outros Autores: | , , , , , |
| Formato: | article |
| Idioma: | eng |
| Publicado em: |
2019
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| Assuntos: | |
| Texto completo: | https://doi.org/10.1038/s41467-018-05071-1 |
| País: | Portugal |
| Oai: | oai:run.unl.pt:10362/67798 |