Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome

Angelman syndrome (AS) is a neurodevelopmental disorder caused by loss of function of the maternally inherited Ube3a neuronal protein, whose main features comprise severe intellectual disabilities and motor impairments. Previous studies with the Ube3am-/p+ mouse model of AS revealed deficits in syna...

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Bibliographic Details
Main Author: Moreira-de-Sá, Ana (author)
Other Authors: Gonçalves, Francisco Q. (author), Lopes, João P. (author), Silva, Henrique B. (author), Tomé, Ângelo R. (author), Cunha, Rodrigo A. (author), Canas, Paula (author)
Format: article
Language:eng
Published: 2020
Subjects:
Adenosine A(2A) receptor
Angelman syndrome
Hippocampus
Mouse model
Synaptic plasticity
Ube3a
Adenosine
Angelman Syndrome
Animals
Disease Models, Animal
Learning
Memory
Mice
Mice, Inbred C57BL
Neuronal Plasticity
Online Access:http://hdl.handle.net/10316/101263
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/101263

Internet

http://hdl.handle.net/10316/101263

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