Multi-Omic profiling of macrophages treated with phospholipids containing Omega-3 and Omega-6 fatty acids reveals complex immunomodulatory adaptations at protein, lipid and metabolic levels

In recent years, several studies have demonstrated that polyunsaturated fatty acids have strong immunomodulatory properties, altering several functions of macrophages. In the present work, we sought to provide a multi-omic approach combining the analysis of the lipidome, the proteome, and the metabo...

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Bibliographic Details
Main Author: Maurício, Tatiana (author)
Other Authors: Aveiro, Susana (author), Guedes, Sofia (author), Lopes, Diana (author), Melo, Tânia (author), Neves, Bruno M. (author), Domingues, Rosário (author), Domingues, Pedro (author)
Format: article
Language:eng
Published: 2022
Subjects:
Macrophage
Omega-6 phospholipid
LPS
Proteomics
Lipidomics
Metabolomics
Online Access:http://hdl.handle.net/10400.1/17983
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/17983

Internet

http://hdl.handle.net/10400.1/17983

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