Highly selective capture of minicircle DNA biopharmaceuticals by a novel zinc-histidine peptide conjugate

The use of minicircle DNA (mcDNA) biomolecules as a pharmaceutical product holds remarkable potential due to their improved therapeutic efficacy in comparison with standard non-viral gene expression vectors. However, mcDNA translation into clinical application is still highly restricted due to the l...

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Bibliographic Details
Main Author: Gaspar, Vítor Manuel Abreu (author)
Other Authors: Cruz, Carla Patrícia Alves Freire Madeira (author), Queiroz, João (author), Pichon, Chantal (author), Correia, Ilídio (author), Sousa, Fani (author)
Format: article
Language:eng
Published: 2018
Subjects:
Minicircle DNA
Affinity interactions
Biopharmaceuticals
Biomimetic peptide
Online Access:http://hdl.handle.net/10400.6/4693
Country:Portugal
Oai:oai:ubibliorum.ubi.pt:10400.6/4693

Internet

http://hdl.handle.net/10400.6/4693

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