Proteotoxic stress in human genome stability

Incorporation of errors during protein synthesis is denominated mistranslation. This compromises the acquisition of a correct final three dimensional structure and consequently the accumulation in the cell of proteins with abnormal conformations. Cells have protein quality control (PQC) mechanisms t...

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Detalhes bibliográficos
Autor principal: Santana, Inês Manuela do Vale (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2014
Assuntos:
Texto completo:http://hdl.handle.net/10773/12606
País:Portugal
Oai:oai:ria.ua.pt:10773/12606